Sadness and loneliness has a greater anti-aging effect than smoking.

A study found that the onset of molecular damage makes age-related frailty and serious diseases worse. Some people age more quickly than others due to their molecular processes being more intensive.Fortunately, employing computational models of ageing can help identify the accelerated rate of ageing before its devastating effects become apparent (ageing clocks). These models can be used to generate anti-aging treatments for both individuals and populations.

The most recent article in Aging-US states that both physical and mental health must be addressed as part of any anti-aging therapy. Scientists from the US and China worked together in an international partnership lead by Deep Longevity to examine the impacts of loneliness, sleep disturbances, and emotional distress on the rate of ageing and discovered a statistically significant relationship.
A novel ageing clock that was tested and verified using blood and biometric information from 11,914 Chinese adults is featured in the article. This is the first ageing clock that has been trained solely on a large Chinese cohort.

People with a history of stroke, liver and lung disease, smokers, and most intriguingly, those in a precarious mental condition, all showed signs of accelerated ageing. It was discovered that one’s biological age was increased more by feeling hopeless, miserable, and alone than by smoking. Living in a rural region and being single are two additional variables associated with ageing more quickly (due to the low availability of medical services).The article’s writers came to the conclusion that the psychological effects of ageing shouldn’t be overlooked in either anti-aging research or real-world applications. Mental and psychosocial states are among the most reliable determinants of health outcomes — and quality of life, according to Stanford University’s Manuel Faria — but they are frequently ignored in contemporary healthcare.

The study offers a plan of action to “slow down or perhaps reverse psychological ageing on a national scale,” according to Alex Zhavoronkov, CEO of Insilico Medicine.An AI-guided mental health web service called FuturSelf.AI, which Deep Longevity introduced earlier this year, is based on an earlier article from Aging-US. The service gives a free psychological evaluation that is handled by AI and generates a detailed report on a user’s psychological age as well as their present and future mental health. “FuturSelf.AI, in combination with the study of older Chinese adults, positions Deep Longevity at the forefront of biogerontological research,” says Deepankar Nayak, CEO of Deep Longevity.

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